Notably, the LFP SWA measured by tetrodes in the local CA1 circuitry showed a tendency toward lower levels during NREM sleep in 4- to 5-month-old APP/PS1 mice but did not reach statistical significance (p = 0.14; Figure 3 H).
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Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models.
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