Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria.

Aging (Albany NY) · 2022 · PMC8791216 · PMID 35020601

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a strong trendno p-value reported

Finally, a strong trend towards increased expression of miR34a-5p and miR31-5p was observed in fibroblasts co-cultured in the presence of lung Prog-Tg ECs presumably due to either paracrine effects or direct secretion and uptake of these miRs ( Supplementary Figure 5E ).

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