Amyotrophic Lateral Sclerosis-Frontotemporal Dementia: Shared and Divergent Neural Correlates Across the Clinical Spectrum.

Neurology · 2022 · PMC8793105 · PMID 34853179

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Functional Connectivity NBS analysis did not show differences in functional connectivity in ALS groups relative to controls, although patients with ALS-ci/bi showed a trend toward an enhanced functional connectivity relative to controls within frontal and basal ganglia areas ( p = 0.06).

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a nonsignificant trendp = 0.08so close (0.05 < p ≤ 0.1)

On the other hand, the bvFTD-like pattern was found to be more frequent neither in ALS-ci/bi nor ALS-FTD compared to ALS-cn, except for a nonsignificant trend ( p = 0.08) within frontal and among frontal-basal ganglia, temporal-occipital areas in ALS-FTD relative to ALS-cn (eTable 5).

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