The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study.

PLoS Med · 2022 · PMC8794090 · PMID 35085228

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

borderline significanceP = 0.055so close (0.05 < p ≤ 0.1)

Genetically predicted Lp(a) was associated at borderline significance with advanced PCa after adjusting for multiple lipid traits (OR = 1.078; 95% CI = [0.999,1.163]; P = 0.055).

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may not be significantno p-value reported

Line 267, Table 2: Did you do any correction for the p-values of the MVMR for multiple testing? The p-values are not very small so I am worried that after correcting for multiple testing, the p-values may not be significant anymore.

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nominally significantno p-value reported

Throughout the results section, nominally significant results are reported.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.