Concomitant Treatment of Hypertensive Patients with Bisoprolol and Perindopril in Routine Clinical Practice: A Post Hoc Analysis of the CONFIDENCE II, PROTECT I, and PROTECT III Observational Studies.

Adv Ther · 2022 · PMC8799572 · PMID 34755324

Europe PMC DOI

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0.0590

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did not reach statistical significanceP = 0.059so close (0.05 < p ≤ 0.1)

Effect of Treatment on Blood Pressure Parameters In the subpopulation of patients receiving perindopril on top of bisoprolol-based therapy (merged data from three studies), a significant SBP decrease from baseline was observed at visit 2 (− 14.7 ± 12.3 mmHg, P < 0.001); the decrease in DBP of -6.7 ± 8.2 mmHg did not reach statistical significance ( P = 0.059).

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