Barely Significant
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Metabolome analysis of key genes for synthesis and accumulation of triterpenoids in Wolfiporia cocos.

Sci Rep · 2022 · PMC8799705 · PMID 35091582

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a decreasing trendno p-value reported
Isoquinoline biosynthesis was significantly enriched in both the H and L strain, with it showing a decreasing trend in both.

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an increasing trendno p-value reported
The biosynthesis of antibiotics, indole alkaloid biosynthesis, inositol phosphate metabolism, and phosphatidylinositol signal system in the H strain decreased, while diterpenoid biosynthesis, propanoate metabolism, and plant hormone signal transduction exhibited an increasing trend.

also in 63,971 other papers

showed a trendno p-value reported
The up-regulated metabolites (including POS and NEG) at 17, 34, and 51 d showed a trend of decreasing at first and then increasing.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.