Heart Failure with Preserved Ejection Fraction: a Pharmacotherapeutic Update.

Cardiovasc Drugs Ther · 2023 · PMC8801287 · PMID 35098432

Europe PMC DOI

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a clear trendno p-value reported

Also, when we compare the drug’s effect across the EF spectrum, we see a clear trend towards the reduction of it’s effect in preventing first HF hospitalization or cardiovascular death as the EF increases [ 27 ].

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of borderline significanceno p-value reported

Though the trial found a trend towards fewer cardiovascular outcomes, favouring candesartan, it was moderate and of borderline significance.

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