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CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells.

Nat Commun · 2022 · PMC8803836 · PMID 35102167

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While GRP78.1x-CAR T cell expansion and viability were slightly lower than for the other CAR constructs, this did not reach statistical significance (Fig. 2c ).

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