While the study by Friedrich and Müller-Goymann illustrated an increased drug loading with higher phospholipid concentrations (e.g., 50%), it has also been demonstrated that this difference may not be hugely significant, e.g., in the work of Chime et al.
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Solidified Reverse Micellar Solution- (SRMS-) Based Microparticles for Enhanced Oral Bioavailability and Systemic Antifungal Efficacy of Miconazole Nitrate in Immunocompromised Mice.
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