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Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.

Mol Neurodegener · 2022 · PMC8811969 · PMID 35109920

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showed a trendno p-value reported
In the cortex, male APPPS1;FE3Cre + mice showed no difference in Aβ levels, while female APPPS1;FE3Cre + mice showed a trend towards lower Aβ plaque load compared to female APPPS1;FE3Cre- mice (Fig. 3 B).

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