In the cortex, male APPPS1;FE3Cre + mice showed no difference in Aβ levels, while female APPPS1;FE3Cre + mice showed a trend towards lower Aβ plaque load compared to female APPPS1;FE3Cre- mice (Fig. 3 B).
← all excerpts
Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
1
—
—