Predictive value of tumor mutational burden for immunotherapy in non-small cell lung cancer: A systematic review and meta-analysis.

PLoS One · 2022 · PMC8812984 · PMID 35113949

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

High TMB was associated with longer PFS in patients treated with only PD-L1 inhibitors (HR = 0.76, 95%CI: 0.57–1.02, P = 0.070), but the association did not reach statistical significance which may be due to substantial between-study heterogeneity.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.