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SMAD4 mutations do not preclude epithelial-mesenchymal transition in colorectal cancer.

Oncogene · 2022 · PMC8816731 · PMID 34857888

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Yet, while their expression was not affected by SMAD4 status in CMS1-3, EMT-TF expression in CMS4 samples tended to be lower in SMAD4 mut tumors compared to SMAD4 wt , albeit this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.