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A mitochondria cluster at the proximal axon initial segment controls axodendritic TAU trafficking in rodent primary and human iPSC-derived neurons.

Cell Mol Life Sci · 2022 · PMC8816743 · PMID 35119496

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The mitochondrial cluster was observable throughout our examined time course, with ~ 33% of neurons displaying it already after 7 DIVs and an increase in the proportion of AIS-mitocluster positive neurons to 43% in older neurons, although these results did not reach statistical significance.

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