Out of 13 patients having at least 2 mutations in separate genes, 8 patients showed a trend that was similar to the mutation in TP53 , the other 4 genes showed a different trend: KEM-016 only had one detectable mutation in plasma at postoperative day 1 ( TP53 ) the other mutation was only detected in tissue.
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Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer.
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