Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy.

Nucleic Acid Ther · 2021 · PMC8823675 · PMID 34061681

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a clear trendno p-value reported

A clear trend in decreased Aβ40 levels was found 4 days after 33-mer AON transfection, whereas Aβ40 levels transfected with 33-mer SCR1 and 33-mer SCR2 AONs were similar to untransfected cells ( Fig. 3B ).

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