Patient-reported outcomes and target effect sizes in pragmatic randomized trials in ClinicalTrials.gov: A cross-sectional analysis.

PLoS Med · 2022 · PMC8824332 · PMID 35134080

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a significant trendno p-value reported

Prevalence of PROs was not significantly associated with other stakeholder engagement, and there did not seem to be a significant trend toward improvement over time.

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