Specificity of time- and dose-dependent morphological endpoints in the fish embryo acute toxicity (FET) test for substances with diverse modes of action: the search for a "fingerprint".

In contrast, LC 10 values for either substance did not show any significant impact over time, although there was a clear trend for colchicine: For individuals exposed to colchicine, the LC 50 also varied significantly between 48 and 96 hpf ( ρ = 0.019), yet without a significant difference between 48 and 72 hpf or 72 and 96 hpf.

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