Epithelial Ablation of Miro1/Rhot1 GTPase Augments Lung Inflammation by Cigarette Smoke.

Pathophysiology · 2021 · PMC8830451 · PMID 35366248

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showed a trendno p-value reported

CS-exposed Rhot1 epithelial cell-specific KO (Rhot1 CreCC10 ) mice showed a significant increase in the levels of MCP-1, IL-6, IL-1α, IL-12p40, KC and MIP-1α, whereas TNF-α and IL-13 showed a trend in increased levels by CS ( Figure 2 ).

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an increasing trendno p-value reported

Interestingly, a significant increase in the levels of IL-1α with an increasing trend in other mediators MIP-1α, IL-6, MCP-1, KC, TNF-α, IL-13, and IFN-γ were observed in WT (Rhot1 fl/fl ) CS groups.

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