IGF-I and Hyaluronic Acid Mitigate the Negative Effect of Irradiation on Human Skin Keratinocytes.

There was a higher expression of TNF and a clearly significant higher expression of IL6 and MKI67 after treatment with 1 mg/mL H-HA/L-HA compared to the control in both irradiation groups (7.13- and 5.76-fold after 2 Gy irradiation, 4.40- and 5.50-fold after 5 Gy irradiation) ( Figure 5 b,c). 3.4.

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