Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury.

The renal hepcidin KO was shown to be successful as both the renal hepcidin DNA product and mRNA expression were reduced in hepcidin flox mice ( Figure 3 A), although the difference in mRNA expression between the hepcidin wt and hepcidin flox mice did not reach statistical significance.

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