Gene-Interaction-Sensitive enrichment analysis in congenital heart disease.

BioData Min · 2022 · PMC8841104 · PMID 35151364

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 0.001actually significant

Correlation analysis For the CHD data, we evaluated the overall correlation between the gene ranks for each analysis in both cohorts, all of which were highly significant (p < 0.001, Table 1 ).

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nominally significantp < 0.05actually significant

While none of the GO terms from the trio univariate GSEA met the FDR significance threshold, nominally significant (p < 0.05) pathways suggest some overlap with Cohort 1 results, including neuron recognition , cerebral cortex cell migration and axonal fasciculation and GO terms related to.

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