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Liraglutide attenuate central nervous inflammation and demyelination through AMPK and pyroptosis-related NLRP3 pathway.

CNS Neurosci Ther · 2022 · PMC8841291 · PMID 34985189

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In the EAE situation, those cytokines mRNA expressions were all upregulated 5–23‐fold compared with the Ctrl group, while Lira intervention downregulated them (among them, TNF‐α did not reach statistical significance).

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