A novel <i>STK11</i> gene mutation (c.388dupG, p.Glu130Glyfs∗33) in a Peutz-Jeghers family and evidence of higher gastric cancer susceptibility associated with alterations in STK11 region aa 107-170.

Genes Dis · 2022 · PMC8843985 · PMID 35224145

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showed a trendno p-value reported

Thus, the results of our meta-analysis showed a trend toward GC susceptibility in patients with nonsense and frameshift mutations in STK11 region aa 107–170 compared with patients harboring mutations in the remaining kinase catalytic region.

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