showed a trendP = 0.07
Indeed, Rb ∆K7 MEFs were significantly more resistant to GW8510 ( P = 0.008) and showed a trend toward significant resistance to a pan‐CDK inhibitor, AT‐751, which targets CDK2, as well as CDK1, CDK4, CDK6, and CDK5 ( P = 0.07; Fig 3B ).