Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model.

BMC Cancer · 2022 · PMC8848646 · PMID 35172762

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Further quantitative analysis of T cell subsets showed a trend towards reduced cytotoxic T cell (CD8 + , Fig. 5 C) infiltration in the chemotherapy treated groups; however, CD8 + T cell preservation in the TME of the Gem/Ab group appeared to be superior to tumors from FFX treated mice.

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