Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups.

Med Chem Res · 2022 · PMC8853087 · PMID 35194363

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

showed a trendno p-value reported

According to the structure-activity relationship study, the N , N -dimethylcarbamate derivative 2b (18.45 μM), the N , N -diethyl carbamate analogue 2d (13.02 μM), and the N , N -diisopropylcarbamate substitute 2g (9.09 μM) showed a trend toward more potent anticancer activity against NCI-H1299 cells with increasing lipophilicity of the carbamate residues in the molecule.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.