Considerations and practical implications of performing a phenotypic CRISPR/Cas survival screen.

PLoS One · 2022 · PMC8853573 · PMID 35176052

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closest p · 0.2× alpha

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did not reach statistical significance-log10(p-value) >2actually significant

MED16 and MED24 also showed some enrichment, but most guides did not reach statistical significance (LFC > 1, -log10(p-value) >2) in most of the screens.

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