Although our sample size was insufficient to achieve statistical significance, a clear trend was observed with 100% 90-day survival in low NET producers (neutrophil NET release < cohort median), compared with only 60% 90-day survival in high NET producers (neutrophil NET release > median of cohort) ( Figure 6A ).
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A functionally distinct neutrophil landscape in severe COVID-19 reveals opportunities for adjunctive therapies.
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