Barely Significant
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Impact of molecular alterations on quality of life and prognostic understanding over time in patients with incurable lung cancer: a multicenter, longitudinal, prospective cohort study.

Support Care Cancer · 2022 · PMC8857091 · PMID 34877613

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a favorable trendno p-value reported
NCCN DT and PHQ-4 scores were comparable at baseline between the two groups, but they showed a favorable trend for patients with molecular alterations over time (NCCN DT at T1 3.3 vs 5; at T2 2.7 vs 4.5; at T3 3.7 vs 4.5; PHQ-4 at T1 2.3 vs 4.1; at T2 1.7 vs 3.6; at T3 2.2 vs 3.6).

also in 1,335 other papers

a significant trendno p-value reported
QoL scores improved over time, with a significant trend for DT, PHQ-4, and SCNS-SF-34.

also in 9,775 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.