Biopsy data In situ zymography showed a trend for MMP activity to be reduced in SSc biopsy tissue with increasing skin score, suggesting that skin-resident enzymes may have been utilised to facilitate remodelling in line with increasing skin score (Table 2 ).
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Polarisation-sensitive optical coherence tomography measurement of retardance in fibrosis, a non-invasive biomarker in patients with systemic sclerosis.
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