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The MDM2 antagonist idasanutlin in patients with polycythemia vera: results from a single-arm phase 2 study.

Blood Adv · 2022 · PMC8864654 · PMID 34933330

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showed a trendno p-value reported
Idasanutlin treatment showed a trend toward improvement in patient-reported outcomes, with a ≥50% reduction in symptom burden per MPN-SAF TSS experienced by 43% of patients at week 32.

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