Potential Role of Intracranial Mast Cells in Neuroinflammation and Neuropathology Associated with Food Allergy.

In addition to the changes in the brain histamine levels, the expression of H3R showed an increasing trend in the frontal cortex of the BLG-sensitized mice, although the difference did not reach statistical significance ( p = 0.07; Figure 10 B).

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PLP1, another structural protein of myelin, showed a decreasing trend, though it did not reach statistical significance ( Figure 14 B; p = 0.08).

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Such time-dependent differences between the groups were also present with the duration and number of immobile episodes ( Figure S1C,D ) but did not reach statistical significance ( Figure 3 C,D).

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