Magnetic Resonance Imaging as a Prognostic Disability Marker in Clinically Isolated Syndrome and Multiple Sclerosis: A Systematic Review and Meta-Analysis.

Diagnostics (Basel) · 2022 · PMC8871297 · PMID 35204361

Europe PMC DOI

hedged sentences

0.0070

closest p · 0.1× alpha

0.0070

boldest claim

The sentences

a significant trendp = 0.007actually significant

There was a significant trend for the development of SPMS to be associated with a higher T2 lesion volume increase over 20 years than in patients who remained RRMS ( p = 0.007), and the T2 lesion volume increase in patients diagnosed with SPMS appeared to be higher than in those with RRMS ( p = 0.08) [ 10 ].

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highly significantno p-value reported

Four or more lesions at baseline showed a highly significant association with EDSS 3 and EDSS 6, with a pooled OR of 4.10 and 4.3, respectively.

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