Treatment with 0.3 mg kg −1 COL significantly suppressed ankle swelling at 12 h ( p < 0.05, F = 6.307) in comparison with MC group, but the effects did not reach statistical significance ( p < 0.05, F = 0.04 to 0.22) at 4, 24 and 48 h.
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<i>N</i>-Butyrylated hyaluronic acid ameliorates gout and hyperuricemia in animal models.
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