PT (39%) and KO2 (52%) neurons had less neurofilament positive axons than control (72%) ( p < .05, Fisher’s exact), whereas KO1 did not reach statistical significance with 62% of axons containing neurofilaments ( Figure 3D ).
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Neurofilament Light Regulates Axon Caliber, Synaptic Activity, and Organelle Trafficking in Cultured Human Motor Neurons.
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