Clozapine Induces an Acute Proinflammatory Response That Is Attenuated by Inhibition of Inflammasome Signaling: Implications for Idiosyncratic Drug-Induced Agranulocytosis.

Toxicol Sci · 2022 · PMC8883353 · PMID 34935985

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

did not reach statistical significancep = .054so close (0.05 < p ≤ 0.1)

Splenic levels of IL-1β trended toward an increase at both 1.5 and 3 h but did not reach statistical significance ( p = .054 and p = .061, respectively) ( Figure 4G ).

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