In contrast, six of the ten selected gene of the SLC family (Slc5a2, Slc16a4, Slc16a14, Slc22a7, Slc22a13 and Slc34a3) showed a significant downregulation at mRNA level following Pals1 depletion, whereas the other tested SLC genes (Slc10a2, Slc22a2, Slc22a8 and Slc39a5) showed a trend toward downregulation, but no significance ( Figure 2A ).
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Impact of Pals1 on Expression and Localization of Transporters Belonging to the Solute Carrier Family.
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