Long-Term Effectiveness of Oral Ferric Maltol vs Intravenous Ferric Carboxymaltose for the Treatment of Iron-Deficiency Anemia in Patients With Inflammatory Bowel Disease: A Randomized Controlled Noninferiority Trial.

25-29 A Bayesian network meta-analysis of these trials showed a significant superiority of ferric carboxymaltose over traditional oral ferrous iron (odds ratio, 1.9; 95% credible interval, 1.2-3.2), whereas other IV formulations did not reach statistical significance. 29 Only 1 trial used IV ferric carboxymaltose, which was compared with oral ferrous sulfate 100 mg twice daily over 12 weeks. 26 Improvements in Hb were 3.7 and 2.8 g/dL in patients receiving IV ferric carboxymaltose and oral ferrous sulfate, respectively.

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