Long-term safety and efficacy of ferric citrate in phosphate-lowering and iron-repletion effects among patients with on hemodialysis: A multicenter, open-label, Phase IV trial.

PLoS One · 2022 · PMC8893642 · PMID 35239732

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Slope was used to represent the time trend of study outcomes; a positive value indicates an increasing trend while a negative value indicates a decreasing trend.

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showed a trendno p-value reported

The serum phosphorus was sustainably controlled in long term, while the increase of iron storage showed a trend of plateau after 3-6 months of treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.