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Associations of Alcohol Consumption and Smoking With Disease Risk and Neurodegeneration in Individuals With Multiple Sclerosis in the United Kingdom.

JAMA Netw Open · 2022 · PMC8895260 · PMID 35238934

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Although these findings did not reach statistical significance and need to be interpreted with caution, these may still represent clinically important processes, given their large effect sizes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.