ERAP1 is a critical regulator of inflammasome-mediated proinflammatory and ER stress responses.

BMC Immunol · 2022 · PMC8895631 · PMID 35246034

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did not reach statistical significanceno p-value reported

We also noted increased trends towards increased production of other proinflammatory cytokines including IL-1α, IL-2, GM-CSF, and EOTAXIN in colon homogenates of DSS-treated ERAP1 −/− mice as compared to DSS-treated WT controls; however, these trends did not reach statistical significance (data not shown).

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