Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease.

Hsa_circ_0002564 shows weak correlations with the other two circ PSEN1 species even though some of them are nominally significant (with hsa_circ_0008521 only in the discovery dataset—r 2 = 0.25, p = 0.02, and with hsa_circ_0003848 in the discovery—r 2 = 0.26, p = 0.01 and in the BM22 of the MSBB dataset—r 2 = 0.31, p = 8.15 × 10 –05 ).

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