LncRNA CCAT1 facilitates the proliferation, invasion and migration of human laryngeal squamous cell carcinoma cells <i>via</i> the miR-218-5p/BMI1.

PeerJ · 2022 · PMC8898548 · PMID 35261819

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We subsequently verified the targeted relationship between CCAT1 and miR-218-5p by dual-luciferase assay, which exhibited decreased luciferase activity in cells transfected with miR-218-5p mimic and CCAT1-WT while no significant difference was apparent in cells transfected with miR-218-5p mimic and CCAT1-MUT ( p < 0.01, Fig. 2E ).

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