COPD mortality and exacerbations in the placebo group of clinical trials over two decades: a systematic review and meta-regression.

ERJ Open Res · 2022 · PMC8899495 · PMID 35265703

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a decreasing trendno p-value reported

For commercial reproduction rights and permissions contact permissions@ersnet.org Abstract A decreasing trend in exacerbation rates has been observed in COPD.

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did not reach statistical significanceno p-value reported

This decline is of similar magnitude to the decline in exacerbation rate but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.