<i>CHEK2<sup>p.I157T</sup></i> Mutation Is Associated with Increased Risk of Adult-Type Ovarian Granulosa Cell Tumors.

Cancers (Basel) · 2022 · PMC8909001 · PMID 35267514

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hedged sentences

0.0520

closest p · 1.0× alpha

0.2067

boldest claim

The sentences

marginally statistically significantp -value = 0.052so close (0.05 < p ≤ 0.1)

We found this association between the FOXL2 p.C134W mutation status and FOXL2 positivity by IHC to be marginally statistically significant (mid- p -value = 0.052).

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did not reach statistical significancep = 0.2067not close (p > 0.1)

When both CHEK2 founder mutations are considered, mutations carriers’ median age at diagnosis is 43 years and thus lower than the median age at diagnosis of 58.5 years in patients with confirmed absence of both founder mutations; however, the difference did not reach statistical significance (Gehan–Breslow–Wilcoxon test p = 0.2067). 3.2.

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