Human Cytomegalovirus Seropositivity and Viral DNA in Breast Tumors Are Associated with Poor Patient Prognosis.

The risk of reduced relapse-free survival was 1.55 times higher in the HCMV IgG-positive patients, but this did not reach statistical significance (95% CI 0.81−2.96, p = 0.185, Figure S2 ). 3.5. mRNA Expression of HCMV IE1 Was Not Detected in any Human Breast Tumors or Normal Breast Tissue The expression of HCMV IE1 mRNA was examined in the same set of human breast tumors ( n = 136) and normal breast tissues ( n = 10).

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