[ 90 ], who observed a highly significant prolongation of the CT value in INTEM and in EXTEM using apixaban in supratherapeutic concentrations.
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"In Less than No Time": Feasibility of Rotational Thromboelastometry to Detect Anticoagulant Drugs Activity and to Guide Reversal Therapy.
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The sentences
However, when comparing trough (121.7 ± 13.5 ng/mL) and peak samples (181.9 ± 23.6 ng/mL), there was a trend towards prolonged peak CT for all three reagents (INTEM, EXTEM, FIBTEM), but the differences did not reach statistical significance.