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Prevalence of sleep disturbance and the association between poor disease control in people with ankylosing spondylitis within the Australian clinical setting (ASLEEP study): a real-world observational study using the OPAL dataset.

Clin Rheumatol · 2022 · PMC8913462 · PMID 34825268

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There were some treatment-related differences in the propensity score matched population: the mean MAPI index was higher in those with IL-17Ai at index (IL-17Ai 0.4 ± 0.3 and TNFi 0.3 ± 0.2, p = 0.046), and the proportion at risk of sleep apnoea based on the MAPI score was higher in those treated with IL-17Ai than those treated with TNFi (66% vs 54%, p = 0.051), although this did not reach statistical significance.

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