Barely Significant
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<i>ACE2</i> and <i>TMPRSS2</i> SNPs as Determinants of Susceptibility to, and Severity of, a COVID-19 Infection.

Br J Biomed Sci · 2022 · PMC8915702 · PMID 35996506

Europe PMCDOI
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weakly significantno p-value reported
The latter also suggest that sex may have a role in the pathogenicity of the TMPRSS2 SNPs, citing differences in gene responses to androgens, so being linked to sex polymorphism-specific effects, as TMPRSS2 is expressed in androgen-sensitive tissues, and to some extent, the weakly significant effect of sex on disease severity in our study may reflect this proposition.

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