The PLS-DA model built using EM clustering was also affected by the excreted amount of metabolites, but it showed a trend towards a different metabolic profiles, as a group of individuals was characterized by a relatively high excretion of 5-(4′-hydroxyphenyl)-γ-valerolactone and HPP derivatives, while the other by a reduced production of these metabolites.
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Metabotypes of flavan-3-ol colonic metabolites after cranberry intake: elucidation and statistical approaches.
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